Product FeaturesThe mechanism of action of HAMSYL is based on the selective killing of leukemic cells due to depletion of plasma asparagine. Some leukemic cells are unable to synthesize asparagine due to a lack of asparagine synthetase and depend on an exogenous source of asparagine for survival. The depletion of asparagine, which results from treatment with the enzyme L-asparaginase, kills the leukemic cells. Normal cells, however, are less affected by depletion because of their ability to synthesize asparagine.
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INFORMATIONThis blog is designed to provide information about acute lymphoblastic leukemia as well as treatment options and support for both patients and medical staff. All rights reserved to the group Asparaginase Pegilada. ArchivesCategories |